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Feb042014

Furiex Treatment Meets Late-stage Study Goals









Food and Drug Administration and the European Medicines Agency. The treatment is intended to ease abdominal pain for patients with diarrhea-prominent irritable bowel syndrome, and improve stool consistency. Two studies involving more than 2,400 patients compared different doses of the treatment against a placebo. The company said about 28 million patients are affected by this particular form of irritable bowel syndrome in the United States and major European markets. The Furiex treatment had received an FDA fast-track designation, which is designed to speed up the development and review of drugs that treat diseases with significant and unmet medical need. The company said it was on track to apply for the drug's approval by the end of the second quarter.

continue http://money.msn.com/business-news/article.aspx?feed=AP&date=20140204&id=17319425














Furiex Shares Double as Irritable Bowel Drug Succeeds in Trials






(FURX) more than doubled in New York trading after its experimental drug alleviated diarrhea and abdominal pain caused by irritable bowel syndrome in two studies. Furiex surged to $111.41 at 10:05 a.m. New York time, its biggest intraday jump since the Morrisville, North Carolina-based companys shares began trading in June 2010. The studies were in the last of three rounds generally needed for regulatory clearance. The drug eluxadoline met targets for improvements in stool consistency and abdominal pain that were developed in conjunction with U.S. and European regulators, the company said today. Furiex will apply for approval in June, Chairman Fred Eshelman said in an investor call today. He estimated annual sales of $750 million to $1 billion. By our math, it looks like a pretty doggone good market, Eshelman said on the call, noting that there is only one currently approved drug available in the U.S.

find more info http://www.bloomberg.com/news/2014-02-04/furiex-shares-double-as-irritable-bowel-drug-succeeds-in-trials.html







Experimental IBS Drug Eluxadoline Succeeds In Large Trials






"We believe that there are a lot of patients out there who need this drug. There is a huge unmet need," Furiex Chief Medical Officer June Almenoff said in a telephone interview. Currently approved drugs for IBS address constipation associated with the disorder, but there are few options for diarrhea predominant IBS. Furiex founder and chairman Fred Eshelman said he believes the drug has the potential for blockbuster sales, which he defined as annual sales of between $750 million and $1 billion. Eluxadoline was tested at two doses against a placebo over the course of 12 weeks to meet requirements by the U.S. Food and Drug Administration, and for 26 weeks for European health regulators, in Phase III studies involving 2,428 patients, Furiex said. For the combined goal of improvement in abdominal pain and stool consistency for at least half the days in the study, eluxadoline achieved a statistically significant improvement at the 100 milligram and 75 mg doses through 12 weeks in both studies. On the 26-week measure, the higher dose succeeded in both studies but the lower dose missed statistical significance in one of the two trials, according to initial results released by the company. The success appeared to be driven by the percentage of patients reporting improvements in diarrhea, which ranged from 30 percent to 37 percent versus 22 percent and 20.9 percent for the placebo groups.

going here http://www.huffingtonpost.com/2014/02/04/ibs-drug-eluxadoline-irritable-bowel-syndrome_n_4722058.html




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Feb042014

Frostbite



Hypothermia Is The Condition Of Developing An Abnormally Low Body Temperature.

 Hypothermia is the condition of developing an abnormally low body temperature. Frostbite and hypothermia are both cold-related medical emergencies. The condition has long been recognized. A 5000-year-old pre-Columbian mummy discovered in the Chilean mountains offers the earliest documented evidence of frostbite.

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Hypothermia Is The Condition Of Developing An Abnormally Low Body Temperature.



CDC Detectives Respond to Disease Outbreaks



 Originally there were far more questions than answers: Is it contagious? Is it somehow related to West Nile Virus ? Dengue fever ? Influenza? No one knew for sure. Doctors working in the Social Security hospital recognized and began to track a pattern of sickness; diarrhea and feverprogressed to acute kidney failure , paralysis, and death.

description http://www.emedicinehealth.com/guide.asp?s=rss&a=176524&k=emedicinehealth



Hypothermia Is The Condition Of Developing An Abnormally Low Body Temperature.



Fingernails Yield Clues to Limb Regeneration



 The researchers knew that laying down new nerve cells was crucial for limb regeneration in amphibians, so they wanted to examine their role in mammals. When they removed nerves from the mice's toe tips prior to clipping them, they found that the toe tips failed to regenerate. Additional experiments revealed that nerve removal decreased the level of a growth factor that causes cells to grow and multiply. From their results, Ito's team concluded that the Wnt pathway triggers digit tip regeneration by signaling the formation of new nail from stem cells found at the base of the nail.

try this out http://www.emedicinehealth.com/guide.asp?s=rss&a=176490&k=emedicinehealth


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Feb022014

Grief Is A Natural Journey Not A Prozac Deficiency



Grief, Which Is A Very Normal Response, Is A Journey Yet Psychiatrist And Doctors Are Prescribing Harmful Medications To Stop The Grief Process.

 Topix  43 Year Old with with Schizophrenia Persevering

Grief, Which Is A Very Normal Response, Is A Journey Yet Psychiatrist And Doctors Are Prescribing Harmful Medications To Stop The Grief Process.

43 Year Old with with Schizophrenia Persevering8 hrs ago | Posted by: roboblogger | Full story: Rocklin and Roseville TodayAccording to the National Institutes of Health, paranoid schizophrenia is a "mental illness that involves false beliefs of being persecuted or plotted against."Type in your comments belowNameYou are currently logged in as . Not ?Name 

Grief, Which Is A Very Normal Response, Is A Journey Yet Psychiatrist And Doctors Are Prescribing Harmful Medications To Stop The Grief Process.

 Characters left: 4000       Type the numbers you see in the image on the right:Please note by clicking on "Post Comment" you acknowledge that you have read the Terms of Service and the comment you are posting is in compliance with such terms. Be polite. Inappropriate posts may be removed by the moderator. Send us your feedback .

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43 Year Old with with Schizophrenia Persevering



 Type in your comments below Name You are currently logged in as . Not ? Name Characters left: 4000 Type the numbers you see in the image on the right: Please note by clicking on "Post Comment" you acknowledge that you have read the Terms of Service and the comment you are posting is in compliance with such terms. Be polite. Inappropriate posts may be removed by the moderator.

browse around here http://www.topix.com/health/depression/2014/02/copd-often-leads-to-depression?fromrss=1



COPD often leads to depression



 TopixGrief is a Natural Journey not a Prozac DeficiencyGrief is a Natural Journey not a Prozac Deficiency13 hrs ago | Posted by: roboblogger | Full story: Examiner.comSince when did a normal response require an antidepressant? Grief, which is a very normal response, is a journey yet psychiatrist and doctors are prescribing harmful medications to stop the grief process.

great post to read http://www.topix.com/health/depression/2014/02/grief-is-a-natural-journey-not-a-prozac-deficiency?fromrss=1


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Jan312014

Approved Food

     

       The Coeliac, D H and Gluten Free Message Board[ Post a Response | The Coeliac, D H and Gluten Free Message Board ]When posting messages that contain useful information please only use smilies at the start and end of the message to make it easier to copy it to the supplementary board. It is even more helpful if you post a copy of useful information on the supp board yourself.

Friday Joke Posted By Steve On 31/1/2014, 9:37:10 81.100.68.x There Comes A Time When A Woman Just Has To Trust Her Husband...

Friday photographPosted by Lily on 31/1/2014, 8:40:22    

Bought Some Kelkin Lemon Cake, Co-op Choc Cookies And Some Gf Instant Rice Noodles - Handy For Lunch In Work.

 
 92.18.6.x

learn more here http://members2.boardhost.com/glutenfree/msg/1391157622.html



Friday joke



 The Coeliac, D H and Gluten Free Message Board [ Post a Response | The Coeliac, D H and Gluten Free Message Board ] When posting messages that contain useful information please only use smilies at the start and end of the message to make it easier to copy it to the supplementary board. It is even more helpful if you post a copy of useful information on the supp board yourself. Friday joke Posted by Steve on 31/1/2014, 9:37:10 81.100.68.x There comes a time when a woman just has to trust her husband... For example... A wife comes home late at night, and quietly opens the door to her bedroom. From under the blanket she sees four legs instead of two.

learn more here http://members2.boardhost.com/glutenfree/msg/1391161030.html



Friday photograph



 The Coeliac, D H and Gluten Free Message Board[ Post a Response | The Coeliac, D H and Gluten Free Message Board ]When posting messages that contain useful information please only use smilies at the start and end of the message to make it easier to copy it to the supplementary board. It is even more helpful if you post a copy of useful information on the supp board yourself.Approved FoodPosted by Liz D on 30/1/2014, 21:25:22

It Is Even More Helpful If You Post A Copy Of Useful Information On The Supp Board Yourself.

2.120.36.xApproved Food (short dated food website) have some GF items at the moment.Bought some Kelkin Lemon Cake, Co-Op Choc cookies and some GF instant rice noodles - handy for lunch in work.Haven't tried them yet!

view site? http://members2.boardhost.com/glutenfree/msg/1391117122.html


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Jan302014

Postmenopausal Hormones Containing Estrogen May Reduce Glaucoma Risk



The Most Common Complications Were Pneumonia (27 Percent Of All Complications), Urinary Tract Infections (27 Percent) And Superficial Surgical Site Infections (16 Percent).

 Some prior research has suggested that PMH use may be associated with modestly reduced intraocular pressure (IOP), which suggests PMH may decrease the risk for POAG, according to the study background. The authors examined claims data for women 50 years and older who were enrolled in a managed-care plan for at least four years and had at least two visits to an eye care provider from 2001 through 2009. They evaluated three different classes of PMH (estrogen, estrogen plus progesterone, or estrogen plus androgen) and the risk for POAG. Of the 152,163 eligible enrollees, 2,925 (1.9 percent) developed POAG. Each additional month a woman used a PMH containing estrogen (E) alone was associated with a 0.4 percent reduced relative risk for POAG, according to the study results.

go to this web-site http://www.medicalnewstoday.com/releases/271893.php



Adult tonsillectomy safe with low mortality, complication rates



 Chen, B.A., of the Yale University School of Medicine, New Haven, Conn., and colleagues. Tonsillectomy is one of the most commonly performed otolaryngology procedures but there are few data on the safety of tonsillectomy in adults, according to the study background. The authors identified 5,968 adults in the American College of Surgeons National Surgical Quality Improvement Program who underwent tonsillectomy in 2005 to 2011. Study results indicate the 30-day mortality rate was 0.03 percent, the complication rate was 1.2 percent and the reoperation rate was 3.2 percent. The most common complications were pneumonia (27 percent of all complications), urinary tract infections (27 percent) and superficial surgical site infections (16 percent).

visit the site http://www.medicalnewstoday.com/releases/271896.php



"we Need To Educate The Public, Including Children, About Stroke, Because Often It's The Witness That Makes That 9-1-1 Call; Not The Stroke Victim.



Video game teaches kids about stroke symptoms and calling 9-1-1



 While 67 percent said they would play it at home, only about 26 percent did. Researchers didn't examine why. "We need to educate the public, including children, about stroke, because often it's the witness that makes that 9-1-1 call; not the stroke victim. Sometimes, these witnesses are young children," said Olajide Williams, M.D., M.S., lead author and associate professor of neurology at Columbia University in New York City. The Stroke Hero video game involves navigating a clot-busting spaceship within an artery, and shooting down blood clots with a clot-busting drug.

site http://www.medicalnewstoday.com/releases/271811.php


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